Bones creator Hart Hanson has revealed that Booth and Brennan will be forced to make a big decision in the upcoming season finale. David Boreanaz, who plays Booth, explained that the duo will start to face a crossroads in future episodes.

“We have a much better ender than last year’s,” Boreanaz told TV Guide magazine. “We show how they are going in different directions and how that may affect them when they come back together at the start of season six.”

Emily Deschanel, who stars as Brennan, added: “There are huge obstacles in the way of their deep affection for each other.”

Deschanel also hinted that the pair may decide to change careers, while Hanson explained that Angela will think about moving to Paris. The news would mean that only Camille and Sweets remain at the Jeffersonian Institute.
“The decision Booth and Brennan make affects everybody,” Hanson said. (Source)